Analytical Testing Services

Alkaloid & Natural Isolate Testing
by HPLC

ANALITIKA provides HPLC purity and identity analysis for plant-derived alkaloids and naturally-sourced research isolates, characterizing the analytical composition of submitted compounds regardless of their biological origin.

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3–5 days
COA turnaround
1–3 days
Testing starts within
Public link
On every COA

Examples We Test

Representative compounds in this category

Caffeine
Berberine HCl
Piperine
Quercetin
Curcumin
EGCG (Epigallocatechin Gallate)
Vincamine
Huperzine A
Colchicine
Capsaicin
Sinomenine
Resveratrol

Not listed? Use the Other / Not Listed option when submitting — or contact us before shipping to confirm method suitability.

Verifiable Results

Every COA includes a public verification link

Each Certificate of Analysis carries a unique report number and a shareable link. Anyone you provide the COA to can open that link on the Analitika site and confirm the result matches our sealed laboratory record.

Verify a COA →
✓Unique report number
✓Sealed laboratory record
✓Shareable public link
✓QR code on PDF
✓Hash-based forgery check

Process

How to submit a sample

01

Create a free account

Sign up at the client portal — no commitment, no subscription required.

02

Submit your order

Select your tests, complete the submission form and pay online. Shipping instructions are sent after payment confirmation.

03

Ship your sample

Send your sample to our Ontario lab. Ship your sample in a sealed vial to our Ontario lab.

04

Receive your COA

Testing begins within 1 to 3 business days of sample receipt. COA delivered in 3–5 business days via your portal and email.

Common Questions

Frequently asked questions

Is HPLC well-suited for analyzing plant-derived alkaloids and natural isolates?

Yes. Most alkaloids and natural isolates contain UV-absorbing chromophores — aromatic rings, conjugated double bonds, or heteroaromatic systems — that are readily detected by reversed-phase HPLC with UV detection. The method separates the target compound from co-extractives, related natural congeners, and process impurities, yielding a quantitative chromatographic purity result. This is particularly valuable for confirming that a natural isolate has been adequately purified away from its source matrix.

How does HPLC verify purity in an extract versus a purified isolate?

When a crude or semi-purified extract is submitted, the chromatogram will typically show the primary compound peak alongside additional peaks from co-extractives and structurally related analogs. The primary peak area is reported as a percentage of total integrated area. A higher purity result indicates a more thoroughly purified isolate. The COA documents whether the sample was submitted as a purified isolate or as an extract and notes the chromatographic profile observed.

Can ANALITIKA test colored or pigmented samples like curcumin or berberine?

Yes. Colored matrices such as curcumin or berberine preparations are compatible with HPLC analysis. Sample preparation steps — including appropriate dilution and, where necessary, filtration or centrifugation — typically reduce matrix interference prior to injection. Where the natural pigmentation of the matrix is substantial, detection wavelengths may be adjusted or additional sample cleanup steps applied. Any method modifications are documented in the COA.

What compounds in this category would ANALITIKA decline to test?

ANALITIKA does not test controlled substances listed under the Controlled Drugs and Substances Act (Canada) or analogous regulatory schedules, nor cannabis-derived materials, nor any substance that falls within our declared scope exclusions. If there is any uncertainty about whether a specific natural isolate or alkaloid falls within our testing scope, contact us before submitting — we will advise on acceptability prior to any sample being sent.

Analytical results issued by ANALITIKA COMPOUND TESTING INC. are provided for research-use and research-related purposes only. They describe the sample as received and the analytical methods applied, and constitute analytical data only. ANALITIKA does not determine the safety, suitability for any intended use, or regulatory status of any material tested. These results are not an endorsement, approval, certification, or recommendation of the material for human use or for use in any animal, and must not be presented or relied upon as such. ANALITIKA accepts no responsibility for any use of a tested material beyond the analytical scope of this report.

Ready to test your compounds?

Create a free account to submit samples. COA delivered in 3–5 business days. Ontario, Canada.

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